Arutyunov Sergej Darchoevich,Babaev Elmar Alikper Ogly,Balmasova Irina Petrovna,Gabibov Aleksandr Gabibovich,Mkrtumyan Ashot Musaelovich,Tsarev Viktor Nikolaevich
申请号:
RU20170139861
公开号:
RU2671569(C1)
申请日:
2017.11.16
申请国别(地区):
俄罗斯
年份:
2018
代理人:
摘要:
FIELD: medicine.SUBSTANCE: invention relates to the field of medicine, in particular, dentistry, medical microbiology and endocrinology, and can be used to predict the development of type 2 diabetes in patients with chronic periodontitis. Method includes carrying out metagenomic analysis of at least 4 samples of the microbial biofilm of the periodontal groove, and if samples contain more than 9 % of the Porphyrmonadaceae family in combination with the absence of Sphingobacteriaceae bacteria of the patient with chronic periodontitis, they are considered to be a risk group for the development of type 2 diabetes. Method is confirmed microbiologically or by PCR method.EFFECT: technical result of the invention consists in the determination of such signs associated with chronic periodontitis, that would be pathogenetically associated with insulin sensitivity of cells and would allow to predict the development of type 2 diabetes mellitus.1 cl, 2 dwg, 2 ex