Compositions can be used to stimulate growth of a hair shaft from a hair follicle. These compositions can include methylated polynucleotides useful in treatment of autoimmune diseases or conditions, including those, such as alopecia areata, that result in hair loss.L'invention concerne des compositions utilisées pour le traitement de maladies ou d'affections auto-immunes entraînant la chute des cheveux, par exemple l'alopécie.