Universidade de Santiago de Compostela;Universidad Autónoma de Madrid
发明人:
申请号:
EP17869235.6
公开号:
EP3539971A1
申请日:
2017.11.10
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
The present invention relates to the use of ruthenium(II) complexes for preparing a medicinal product for treating cancer, particularly cancer comprising cancer stem cells. Said ruthenium complexes are capable of selectively metallating guanine quadruplexes, thus resulting in increased expression of the c-MYC oncogene. This increase in the proportion of c-MYC may promote the differentiation of cancer stem cells.