VAKALOPOULOS, ALEXANDROS,BROCKSCHNIEDER, DAMIAN,WUNDER, FRANK,STASCH, JOHANNES-PETER,MARQUARDT, TOBIAS,DIETZ, LISA,LI, MIN JIAN VOLKHART
申请号：
CA2975668
公开号：
CA2975668A1
申请日:
2016.02.02
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The invention relates to n-substituted 8-[(2,6-difluorobenzyl)oxy]-2,6-dimethylimidazo[1,2-a]pyrazin-3-carboxamide derivatives as stimulators of soluble guanylate cyclase (sGC) for the treatment of cardiovascular diseases, such as for example heart insufficiency, angina pectoris, hypertension, pulmonary hypertension, ischaemia, vascular diseases, renal insufficiency, thromboembolic diseases, fibrotic diseases, arteriosclerosis, dementia diseases and erectile dysfunction.
