A novel approach for the quantification of drug in low concentration based on the analysis of fluorescent images with voglibose-an antidiabetic drug chosen for the study.
The present invention discloses a novel method for the quantification of drug in low concentration. The quantification of drug in low concentration is based on the analysis of the Fluorescent Images obtained because of Drug Enzyme Interaction as used in Biosensing. Quantification of drugs in low concentration has challenges as their response to regular methods is low and sometimes not detectable. In this invention an anti-diabetic drug -"Voglibose" is used for the study as it is the lowest concentration drug available in the Pharmaceutical Industry. Because of its low concentration, it suffers poor response and requires expensive instrumentation for its analysis. Dissolution, another important parameter for this drug as it is a reactive drug has no method mentioned in the literature and this invention establishes the method for Dissolution Studies. Thus the invention proves a novel approach for the quantification of the drugs and particularly drugs in low concentration.
