Sobol, Robert E.,Menander, Kerstin B.,Chada, Sunil
申请号：
AU2016349632
公开号：
AU2016349632A1
申请日:
2016.11.07
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
Provided herein are methods and compositions for treating cancer in an individual comprising administering to the individual an effective amount of at least one immune checkpoint inhibitor and a p53 and/or MDA-7 (IL24) gene therapy. Also provided herein are methods of enhancing anti-tumor efficacy by administering an extracellular matrix-degrading protein. Also provided herein are methods of enhancing anti-tumor efficacy by administering metronomic chemotherapy (for agents described above, 5FU+CTX+GM-CSF) in combination with a p53 and/or IL24 gene therapy.
