ALIOS BIOPHARMA, INC.;VERTEX PHARMACEUTICALS, INC.
发明人:
申请号：
ARP130100925
公开号：
AR090456A1
申请日:
2013.03.21
申请国别(地区):
AR
年份:
2014
代理人:
摘要：
Claim 1: a Pharmaceutical composition comprising an effective amount of a compound of the formula: (a), or a pharmaceutically acceptable Salt, hydrate or solvate thereof and two different compounds of the formula (c), or a pharmaceutically acceptable Salt, hydrate Or solvate of the foregoing.Claim 2: the pharmaceutical composition according to claim 1, wherein the compound of formula (a) 1002 is the compound, or a pharmaceutically acceptable Salt, hydrate or solvate thereof, wherein the compound of the formula (c) is the compound 3001 and Gift The Compound of the formula (c) is the compound 3031.Claim 3: the pharmaceutical composition according to claim 1, wherein the compound of formula (a) 1004 is the compound, or a pharmaceutically acceptable Salt, hydrate or solvate thereof, wherein the compound of the formula (c) is the compound and 3001 The Compound of the formula (c) is the compound 3031.Claim 4: a Pharmaceutical composition comprising an effective amount of a compound of the formula: (a), or a pharmaceutically acceptable Salt, hydrate or solvate thereof and a compound of the formula (c) selected among 3015, 3016, 3025 3026 3027, 3028, 3037,,, 3038, 3039, 3040, 3041 3042,, 3048, 3049 3050 3051 3052,,,, 3053, 3054, 3057, 3058 3060, 3059, 3061,3062, 3063, 3064 3065 and 3067 or a pharmaceutically acceptable Salt, hydrate or solvate of the foregoing.Reivindicación 1: Una composición farmacéutica que comprende una cantidad efectiva de lo siguiente: un compuesto de la fórmula (A), o una sal farmacéuticamente aceptable, hidrato o solvato del mismo y dos compuestos diferentes de la fórmula (C), o una sal farmacéuticamente aceptable, hidrato o solvato de lo que antecede. Reivindicación 2: La composición farmacéutica de acuerdo con la reivindicación 1, caracterizada porque el compuesto de la fórmula (A) es el compuesto 1002, o una sal farmacéuticamente aceptable, hidrato o solvato del mismo； en la cual el compuesto de la fórmula (C) es el compuesto 3001 y donde el comp
