TETRAHYDROPROTOBERBERINE COMPOUND, PREPARATION METHOD THEREFOR AND USES THEREOF, AND PHARMACEUTICAL COMPOSITION

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专利权人:

SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMYOF SCIENCES;TOPHARMAN SHANGHAI CO., LTD.

发明人:

Yang HE,Xiangrui JIANG,Jianfeng LI,Yu WANG,Zhen WANG,Weiming CHEN,Fuqiang ZHU,Chunhui WU,Rongxia ZHANG,Jingshan SHEN,Hualiang JIANG

申请号：

US16639394

公开号：

US20200255421A1

申请日:

2018.08.14

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The present invention provides a tetrahydroprotoberberine compound represented by the formula (I), enantiomers, diastereomers, racemates and mixtures thereof, and pharmaceutically acceptable salts, crystalline hydrates and solvates thereof. The invention also provides a method for preparing the compound and the use thereof in the preparation of a medicament for preventing and/or treating central nervous system diseases.

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中国工程科技知识中心

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http://www.ckcest.cn/home/