Nucleoside analogues derived Compounds, Pharmaceutical Composition and its use to treat a viral infection such as adenovirus, coronavirus, flavivirus, HCV, among others.
SMITH, DAVID, BERNARD,DEVAL, JEROME,DYATKINA, NATALIA,WANG, GUANGYI,BEIGELMAN LEONID
申请号：
CL2013000755
公开号：
CL2013000755A1
申请日:
2013.03.20
申请国别(地区):
CL
年份:
2013
代理人:
摘要：
Disclosed herein are phosphorothioate nucleotide analogs, such as thiophosphoroamidate prodrugs and thiophosphates (including &alpha；-thiomonophosphates, &alpha；-thiodiphosphates, and &alpha；-thiotriphosphates), methods of synthesizing phosphorothioate nucleotide analogs, such as thiophosphoramidate prodrugs, and thiophosphates and methods of treating viral infections, such as HCV, cancer, and/or parasitic diseases with the phosphorothioate nucleotide analogs, such as thiophosphoramidate prodrugs, and thiophosphates.COMPUESTOS DERIVADOS DE ANALOGOS NUCLEOSIDOS； COMPOSICION FARMACEUTICA； Y SU USO PARA TRATAR UNA INFECCION VIRAL, TAL COMO ADENOVIRUS, CORONAVIRUS, FLAVIVIRUS, HCV, ENTRE OTROS.
