A direct gastric inhibitory drug, comprising at least one ore containing natural calcium carbonate and / or functionalized synthetic calcium carbonate and at least one pharmaceutical active ingredient, and at least one formulation, Among them, the functional natural or synthetic calcium carbonate is the reaction product of natural or synthetic calcium carbonate with carbon dioxide and one or more acids, which is treated by acid on site and / or supplied with carbon dioxide from external sources. Claim 2: expression consistent with claim 1,where the source of natural calcium carbonate for the preparation of functionalized calcium carbonate (FCC) is selected from the group of marble, calcite, crete, limestone or dolomite and / or mixtures thereof. Claim 3: A formulation according to claim 1, wherein the synthetic calcium carbonate for the preparation of the functionalized calcium carbonate is precipitated calcium carbonate (PCC) comprising aragonitic, vateritic or calcitic mineralogical crystalline forms, especially prismatic, rhombohedral, or scalenohedral or mixtures thereof. Claim 4: A formulation according to any one of claims 1 to 3,The acid selected from hydrochloric acid, sulfuric acid, sulfuric acid, water sulfuric acid, phosphate, phosphate and their acid salts or mixtures is preferably phosphoric acid. Claim 7: a formulation consistent with any substance. In claims 1 to 6, at least one active or inactive pharmaceutical precursor ingredient is selected from synthetic, semi synthetic or natural ingredients or a combination thereof. Claim 8: expression consistent with any claims 1 to 7,At least one of the screenwriters assistants is selected from one of the screenwriters and / or one of the compounds that make the movie. Claim 9: a statement in accordance with claim 8, in which the filmmaker and / or synthesizer may be selected from the water biomembrane preformer or the lipid biomembrane preformer or a combination thereof. Claim 10: a reference in accordance w
