A method of measuring a pulse wave velocity difference in a mobile device includes: obtaining electrocardiogram (ECG) information of an object through a first electrode that contacts a first surface of the object and is included in the mobile device and a second electrode that contacts a second surface of the object and is included in the mobile device obtaining blood flow change information of the first surface and the second surface by using a first optical sensor that contacts the first surface and is included in the mobile device and a second optical sensor that contacts the second surface and is included in the mobile device obtaining pulse wave velocity information to the first surface and pulse wave velocity information to the second surface based on the obtained ECG information and the obtained blood flow change information of the first surface and the second surface and measuring pulse wave velocity difference information based on the pulse wave velocity information to the first surface and the second surface.
