An anchor for an electrical lead or other elongate medical instrument can include an anchor body. The anchor body can define an instrument passageway. The instrument passageway can extend from a first end of the anchor body to a second end of the anchor body. The anchor body can define one or more suture holes in the anchor body. A clamp can be included in or coupled to the anchor body. The clamp can include a first clamping flange and a second clamping flange. The first clamping flange and the second clamping flange can project laterally from the clamp. The clamp can include a clamping cavity extending about the instrument passageway. The clamp can be arranged to close such that changing a distance between the first clamping flange and the second clamping flange causes a dimension of the clamping cavity to decrease and hold the instrument within the instrument passageway.
