PROBLEM TO BE SOLVED: To provide an ultrasonic observation device capable of easily performing a puncture to a region of interest with a puncture needle, an ultrasonic endoscope, an ultrasonic diagnostic system, an operation method of the ultrasonic observation device and an operation program of the ultrasonic observation device.SOLUTION: An ultrasonic observation device which can be connected to an ultrasonic endoscope transmitting an ultrasonic wave to an observation object, receiving the ultrasonic wave reflected on the observation object, allowing a puncture needle to protrude from the tip with insertion of the puncture needle and including a restriction member rising with respect to a prescribed axial direction to restrict the protrusion direction of the puncture needle, comprises: a puncture position detection part which detects the puncture position of the puncture needle at a region of interest within an ultrasonic image on the basis of an ultrasonic signal received by the ultrasonic endoscope； and a restriction member control part which controls the protrusion direction of the puncture needle with the restriction member on the basis of the puncture position detected by the puncture position detection part and the protrusion position of the puncture needle in the ultrasonic image.SELECTED DRAWING: Figure 1
