INHIBITEURS TRICYCLIQUES CONDENSÉS DE MTOR (MAMMALIAN TARGET OF RAPAMYCIN)

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专利权人:

MERCK SHARP & DOHME CORP.

发明人:

MENG, ZHAOYANG,REDDY, PANDURANGA ADULLA, P.,SIDDIQUI, M. ARSHAD,MANDAL, AMIT, K.,LIU, DUAN,ZHAO, LIANYUN,MCRINER, ANDREW

申请号：

EP11820437

公开号：

EP2608668A4

申请日:

2011.08.22

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

This invention relates to novel fused tricyclic compounds under Formula I that are inhibitors of mammalian Target of Rapamycin (mTOR) kinase, which is also known as FRAP, RAFT, RAPT or SEP, and are useful in the treatment of cellular proliferative diseases, for example cancer and other proliferative disorders.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/