Compound 2 - [[5-chloro-2 - [[(6S) - 6 - [4 - (2-hydroxyethyl) piperazin-1-yl] - 1 - methoxy 6,7,8,9 - tetrahydro - 5h benzo [Cancel] - 7 - 2 - il] amino] pyrimidin-4-yl] amino] - N - methyl - benzamide, a dual inhibitor of ALK and FAK； salts of the compound, Pharmaceutical Composition and method of treatment of gliobalstoma Prostat cancer And breast cancer, among others.
SHAWN P. ALLWEIN,MARTIN J. JACOBS,GREGORY R. OTT,LAURENT COURVOISIER
申请号：
CL2014002353
公开号：
CL2014002353A1
申请日:
2014.09.05
申请国别(地区):
CL
年份:
2015
代理人:
摘要：
The present invention provides a compound of formula (I) or a salt form thereof. The compound of formula (I) has ALK and FAK inhibitory activity, and may be used to treat proliferative disorders.<；p>；Compuesto 2-[[5-cloro-2-[[(6S)-6-[4-(2-hidroxietil)piperazin-1-il]-1-metoxi-6,7,8,9-tetrahidro-5H-benzo[7]anulen-2-il]amino]pirimidin-4-il]amino]-N-metil-benzamida； sales cristalinas； composició；n farmacé；utica； y uso de la composició；n en la preparació；n de un medicamento para tratar una afecció；n mediada por ALK o FAK.<；/p>；
