BODO ASMUSSEN,CHRISTOPH SCHMITZ,MICHAEL HORSTMANN,MOHAMMAD SAMETI,ROLF PRACHT,YVES-THORSTEN PRZYBYLLA
申请号:
BRPI0806856
公开号:
BRPI0806856A2
申请日:
2008.01.19
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
The invention relates to a transdermal therapeutic system for the controlled release of water-soluble pharmaceutical active ingredients from an aqueous phase, comprising an occlusive back layer, a central device facing the skin for releasing the agent, an adhesive layer concentrically surrounding the dispensing device and a removable protective film. Said device is made from a stationary solid phase and a liquid phase containing the active ingredient in aqueous solution, the solid phase being formed from a solid with a fleecy or spongy structure.