UNIVERSITE DE LIEGE;UNIVERSITE CATHOLIQUE DE LOUVAIN
发明人:
Rita VANBEVER,Salome KOUSSOROPLIS,Didier CATALDO,Jacques VAN SNICK
申请号:
US15111564
公开号:
US20160331839A1
申请日:
2015.01.16
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to a compound comprising one or more PEG moieties, wherein said compound is a therapeutic agent active for treating a respiratory disease. The present invention also relates to the use of a PEGylated therapeutic agent for treating a respiratory disease. Another object of the invention is a method for enhancing the bioavailability of a therapeutic agent, for enhancing the pulmonary residency of a therapeutic agent and/or for reducing the pulmonary clearance of a therapeutic agent, wherein said methods comprise the PEGylation of the therapeutic agent.