KBP BIOSCIENCES CO LTD;DEDONG ZHANG;CHEN JIANG;AICHEN WANG
发明人:
CHEN JIANG,AICHEN WANG,DEDONG ZHANG
申请号：
IL23958115
公开号：
IL239581A
申请日:
2015.06.22
申请国别(地区):
IL
年份:
2019
代理人:
摘要：
The present invention belongs to the technical field of medicines, and relates to a crystal form of a compound used as a mineralocorticoid receptor antagonist and a preparation method therefor, and in particular, to a method for preparing a compound 2-chloro-4-[(3S,3aR)-3-cyclopentyl-7-(4-hydroxypiperidin-1-carbonyl)-3,3a,4,5-tetrahydro-2H -pyrazolo[3,4-f]quinolin-2-yl]benzonitrile of formula (1)； a crystal form thereof, a preparation method for the crystal form, and the use of the crystal form in the preparation of drugs for the treatment and/or prevention of renal injury or cardiovascular diseases.
