In some embodiments, the disclosure provides for a conjugate comprising: a) a peptide that competes with an Fc fragment of an IgG for binding to an Fc receptor； and b) a targeting moiety that targets molecular aggregates. In some embodiments, the disclosure provides for methods of using the conjugates for treating a disease or disorder associated with aggregate formation.本發明在一些實施例中提供一種結合物，其包含：a)與IgG之Fc片段競爭以結合至Fc受體之肽；及b)靶向分子聚集體之靶向部分。在一些實施例中，本發明提供使用該等結合物治療與聚集體形成有關之疾病或病症之方法。
