International Institute of Cancer Immunology, Inc.;Sumitomo Dainippon Pharma Co., Ltd.
发明人:
Toshio Nishihara,Masashi Gotoh
申请号:
US15054805
公开号:
US09765114B2
申请日:
2016.02.26
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A novel compound of the formula (1):wherein X is a tyrosine residue or a methionine residue; Y and Z each are a single bond or the like; R1 is a hydrogen atom or the like; R2 is a hydroxy group or the like; R3 is a hydrogen atom, alkyl group, amino group or the like; R4 is a hydrogen atom, alkyl group, carboxy group or the like; m is 1 or 2; and n is an integer of 0 to 2, with the proviso that when n is 0, R3 is a hydrogen atom or an alkyl group, or a pharmaceutically acceptable salt thereof, and its use in cancer immunotherapy.