The present invention relates to an apparatus for generating vacuum pulse for medical use. The apparatus for generating vacuum pulse comprises a vacuum cup which is in contact with a part of an object, a pressure controller which is connected to the vacuum cup via a main tube, a pump which provides a negative pressure to the vacuum cup by being connected to the pressure controller via a first tube, and a compressor which provides a positive pressure to the vacuum cup by being connected to the pressure controller via a second tube. The apparatus doesn&primet give unnecessary pain to a patient by putting the positive pressure separately and increase treatment effects by alternately putting both negative and positive pressure on the skin of the patient.COPYRIGHT KIPO 2017대상부위에 접촉되는 진공컵, 진공컵에 주튜브(tube)를 매개로 연결되는 압력 조절 장치, 압력 조절 장치와 제 1튜브를 매개로 연결되어 진공컵에 음압을 제공하는 펌프(Pump) 및 압력 조절 장치와 제 2튜브를 매개로 연결되어 진공컵에 양압을 제공하는 컴프레서(Compressor)를 포함하는 것을 특징으로 하는 의료기용 진공 펄스 발생 장치에 관한 것이다.