The present invention relates to immunosuppressor, preparation method, its purposes and contain their pharmaceutical composition. The present invention provides a new class of compounds that the disease mediated by lymphocytes interactions or disorder, particularly disease related with the receptor-mediated signal transductions of EDG are treated or prevented with what.本發明涉及免疫抑制劑、其製備方法、其用途以及含有它們的藥物組合物。本發明提供了一類新的用於治療或預防由淋巴細胞相互作用介導的疾病或紊亂、特別是與EDG受體介導的信號轉導有關的疾病的化合物。
