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METHODS FOR THE TREATMENT AND PREVENTION OF AGE-RELATED RETINAL DYSFUNCTION
专利权人:
UNIVERSITY OF WASHINGTON
发明人:
MAEDA, TADAO,SAPERSTEIN, DAVID,PALCZEWSKI, KRZYSZTOF
申请号:
CA2714530
公开号:
CA2714530C
申请日:
2009.02.10
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
There is described herein the use of a pharmaceutically effective amount of asyntheticretinal derivative, or use of the same in the preparation of a medicament, fororal administrationto a human subject for the treatment or prevention of age-related impairmentin rod-mediateddark adaptation after light exposure in said subject, on a long termintermittent dosing regimenwherein said synthetic retinal derivative is a 9-cis-retinyl ester or an 11-cis-retinyl ester having astructure represented by Formula I and II, respectively:(see formula I) (see formula II)
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