The present invention relates to compounds of formula (I), or pharmaceutically acceptable acid addition salts thereof, wherein: In this formula, R 1 is selected from the group consisting of hydrogen, halogen, cyano, lower alkyl, halogen-substituted lower alkyl, lower alkoxy, halogen-substituted lower alkoxy or C (O) NH 2 or halogen, cyano or halogen-substituted lower alkoxy Optionally substituted phenyl, or is 2,2-difluorobenzo [d] [1,3] dioxol-5-yl or 6- (trifluoromethyl) pyrazin- (Trifluoromethyl) pyridin-2-yl, 6- (trifluoromethyl) pyrimidin-4-yl, 6- Yl, or 2- (trifluoromethyl) pyrimidin-4-yl； n is 1 or 2； R 2 is halogen, lower alkyl or cyano and R 3 is hydrogen, R 2 is hydrogen and R 3 is halogen, lower alkyl or cyano； X is a bond, -NR ', -CH 2 NH- or -CHR'and； R ' is hydrogen or lower alkyl； Z is a bond, -CH 2 - or -O-； Ar is phenyl or phenyl substituted by one or more substituents selected from the group consisting of 1H-indazol-3-yl, pyridin-2-yl, pyridin- Yl or 1H-pyrazol-5-yl. The compounds of the present invention are useful in the treatment of depression, anxiety disorders, bipolar disorder, ADHD, stress-related disorders, psychotic disorders, schizophrenia, neurological disorders, Parkinson's disease, neurodegenerative disorders, Alzheimer's disease, epilepsy, Can be used to treat hypertension, substance abuse, metabolic disorders, eating disorders, diabetes, diabetic complications, obesity, dyslipidemia, energy expenditure and assimilation disorders, body temperature homeostatic disorders and dysfunctions, sleep and circadian rhythm disorders, or cardiovascular disorders .본 발명은 하기 화학식 I의 화합물 또는 이의 약학적으로 적합한 산 부가 염에 관한 것이다:상기 식에서, R1은 수소, 할로겐, 시아노, 저급 알킬, 할로겐-치환된 저급 알킬, 저급 알콕시, 할로겐-치환된 저급 알콕시 또는 C(O)NH2이거나, 할로겐, 시아노 또는 할로겐-치환된 저급 알콕시로 임의적으로 치환된 페닐이거나, 2,2-다이플루오로벤조[d][1,3]다이옥솔-5-일이거나, 6-(트라이플루오로메틸)피라진-2-일 또는 5-(트라이플루오로메틸)피라진-2-일이거나, 6-(트라이플루오로메틸)피리미딘-4-일이거나, 6-(트라이플루오로메틸)피리딘-3-일이거나, 또는 5-시아노피라진-2-일이거나, 2-(트라이플루오로메틸)피리미딘-4-일이고；n은 1 또는 2이고；R2는 할로겐, 저급 알킬 또는
