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VACCIN A BASE DE PROTEINE 142 DE MEROZOITE P.FALCIPARUM DE RECOM BINAISON
专利权人:
GLAXOSMITHKLINE BIOLOGICALS S.A.;THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY, U.S. ARMY MEDICAL RESEARCH & MATERIAL COMMAND, ON BEHALF OF WALTER REED ARMY INSTITUT
发明人:
LYON, JEFFREY A.,ANGOV, EVELINA,COHEN, JOE D.,VOSS, GERALD
申请号:
CA2462946
公开号:
CA2462946C
申请日:
2002.01.25
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
In this application is the expression and purification of a recombinantPlasmodium falciparum (3D7) MSP-142. The method of the present inventionproduces a highly purified protein which retains folding and disulfidebridging of the native molecule. The recombinant MSP-142 is useful as adiagnostic reagent, for use in antibody production, and as a vaccine.
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