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Polymer compound in which camptothecin derivative and HSP90 inhibitor are combined and use thereof
专利权人:
日本化薬株式会社
发明人:
岡▲崎▼ 麻奈美,丸山 佐起子,増田 亮,山本 啓一朗
申请号:
JP2016504038
公开号:
JP6580030B2
申请日:
2015.02.09
申请国别(地区):
JP
年份:
2019
代理人:
摘要:
Provided are: a polymer compound for efficiently delivering two drugs to an affected area, reducing side effects, and increasing drug efficacy; and an antitumor drug having said polymer compound as an active ingredient. This polymer compound is obtained by ester-bonding a camptothecin derivative and an HSP90 inhibitor to a carboxyl group of a side-chain of a block copolymer obtained by joining a polyethylene glycol segment and a polyglutamic acid segment to one another.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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