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METHODS OF TREATING CANCER AND TESTING MUTATION ZYGOSITY RELATED THERETO
专利权人:
U.S. GOVERNMENT represented by the UNITED STATES DEPARTMENT OF VETERANS AFFAIRS;EMORY UNIVERSITY
发明人:
Brian Paul Pollack,Bishu Sapkota,Charles E. Hill
申请号:
US14077348
公开号:
US20140147411A1
申请日:
2013.11.12
申请国别(地区):
US
年份:
2014
代理人:
摘要:
In certain embodiments, the disclosure relates to methods of treating cancer comprising administering an effective amount a tyrosine kinase inhibitor in combination with an immunotherapy to a subject in need thereof. In certain embodiments, the disclosure relates to methods of treating cancer comprising: i) analyzing both chromosomes in a cell from a subject for the a V600E mutation of BRAF; and ii) determining if both of the chromosomes contain the V600E mutation, then treating the subject comprising the step of administering an effective amount a tyrosine kinase inhibitor in combination with an immunotherapy to the subject.
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