Therapeutic methods using anti-cd200 antibodies

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专利权人:

ALEXION PHARMACEUTICALS INC.

发明人:

YAN YAN,ROTHER RUSSELL P

申请号：

NZ60158011

公开号：

NZ601580A

申请日:

2011.02.11

申请国别(地区):

NZ

年份:

2014

代理人:

摘要：

Disclosed is a bispecific antibody comprising a first antigen combining site that binds to a CD200 protein and a second antigen combining site that binds to a CD20 protein. Also disclosed is the use of an anti-CD200 antibody, or a CD200-binding fragment thereof, in the preparation of a medicament for treating a human afflicted with a cancer that is resistant to therapy with an anti-CD20 therapeutic agent. Further disclosed is the use of an anti-CD200 antibody, or a CD200-binding fragment thereof, in the preparation of a medicament for treating a human afflicted with a cancer comprising cancer cells that express CDS.

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