Marc Centellas Casado,Raúl Insa Boronat,Nuria Reig Bolaño,Núria Gavaldà Batalla
申请号:
US14353459
公开号:
US20140296188A1
申请日:
2012.10.23
申请国别(地区):
US
年份:
2014
代理人:
摘要:
It is provided a catechol-O-methyltransferase (COMT) inhibitor for use in the prevention and/or treatment of trans-thyretin-associated amyloidosis. It is also provided a catechol-O-methyltransferase (COMT) inhibitor for use in the prevention and/or treatment of transthyretin-associated amyloidosis in combination therapy with another COMT inhibitor, a benzoxazole derivative, iododiflunisal, diflunisal, resveratrol, tauroursodeoxycholic acid, doxocycline, or epigallocatechin-3-gallate.