The method of designating the tree-like cell as antigen reactivity the sample of the tree-like cell includes the fact that profit and the said cell the antigen and at least Toll like 1, are made to contact with the receptor stimulus medicine. The tree-like cell which is activated with this method remedies the tumor, brings the expedient which produces the autoimmune disease animal model.樹状細胞を抗原反応性にする方法は樹状細胞の試料を得、該細胞を抗原および少なくとも1のToll様レセプター刺激薬と接触させることを含む。本方法により活性化した樹状細胞は腫瘍を治療し、自己免疫疾患動物モデルを作製する手段をもたらす。