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Storage-Stable Dust-Free Homogeneous Particulate Formulation Comprising At Least One Water-Soluble Vitamin E-Derivative And At Least One Hydrophilic Polymer
专利权人:
发明人:
Felicitas Guth,Karl Kolter,Michael Schönherr,Franz Weber
申请号:
US14036445
公开号:
US20140086993A1
申请日:
2013.09.25
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A storage-stable dust-free homogeneous particulate formulation comprising at least one water-soluble Vitamin E-derivative and at least one hydrophilic polymer. In one embodiment the storage-stable dust-free homogeneous particle formulation, consists of(j) at least one water-soluble Vitamin E-derivative,(k) at least one hydrophilic polymer,(l) optionally additional surface-active substances, and(m) optionally additional pharmaceutical additives, with the proviso, that the sum of (a), (b), (c) and (d) equals 100% by weight of the formulation, and wherein the fines fraction with particle diameters of less than 100 μm is less than 10% by weight.Methods of making the particulate formulation by a spray granulation process are also provided.
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