Anti-antibody or the part of human Ox40 that binds to human Ox40； the non-cellular dominant top of human Ox40 that binds to the above-mentioned antibody； the nucleic acid encoded by the antibody； the vector of the nucleic acid and the Clula Hospedera of the adhesives； the method of Produc Antibody removal, including the composition of the antibody, immunococcus, is used to treat intermediate Ox40 disorders.
ATTINGER, ANTOINE,BLEIN, STANISLAS,BACK, JONATHAN ALBERT,HOU, SAMUEL,LISSILAA, RAMI
申请号：
CL2013003728
公开号：
CL2013003728A1
申请日:
2013.12.26
申请国别(地区):
CL
年份:
2014
代理人:
摘要：
Antagonist Antibody or fragment thereof which binds to the epitope of Human Ox40； extracellular domain of Human Ox40 is joined by Antibody in aforementioned Nucleic Acid Coding； Antibody； vector and host Cell comprising Said nucleic acid and Method for production The composition comprising the Antibody； Antibody； inmunoconjugado use to treat Disorders；Ox40 mediated.LA INVENCIÓN PROPORCIONA A UN ANTICUERPO ANTAGONISTA O FRAGMENTO DEL MISMO QUE SE UNE A OX40 DE HUMANO； EPITOPE DEL DOMINIO EXTRACELULAR DE OX40 DE HUMANO QUE ES UNIDO POR EN ANTICUERPO ANTES MENCIONADO； ACIDO NUCLEICO QUE CODIFICA EL ANTICUERPO； VECTOR Y CÉLULA HOSPEDERA QUE COMPRENDEN DICHO ACIDO NUCLEICO； METODO PARA PRODUCIR EL ANTICUERPO； COMPOSICION QUE COMPRENDE EL ANTICUERPO； INMUNOCONJUGADO； USO PARA TRATAR TRASTORNOS MEDIADOS POR OX40.
