James Butler,Kevin Fitzgerald,Gregory Hinkle,Brian Bettencourt,Huilei Xu
申请号：
US16601681
公开号：
US20200277599A1
申请日:
2019.10.15
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to RNAi agents, e.g., double stranded RNAi agents, targeting the insulin-like growth factor binding protein, acid labile subunit (IGFALS) gene or the insulin-like growth factor 1 (IGF-1) gene, methods of using such double stranded RNAi agents to inhibit expression of an IGFALS gene or an IGF-1 gene, and methods of treating subjects having an IGF system-associated disorder.
