Environmental sanitizing device including a frame housing a disinfectant liquid reservoir and supporting a nozzle, the nozzle associated with a generation system of an air flow within which a plurality of disinfectant liquid particles are suspended to sanitize a closed environment in which the device can be positioned the nozzle is movable with respect to the frame, and associated with positioning system controlled by a control unit for orientation of the nozzle with respect to at least two mutually perpendicular axes, preferably around a first vertical axis and around a second horizontal axis to automatically orient the nozzle in desired direction with respect to the frame during a sanitization step, the nozzle coupled with at least one distance detector able to determine distance between the nozzle and an obstacle facing the nozzle.