BUNT, ANTONIUS MARTINUS GUSTAVE,VAN TELLINGEN, OLAF
申请号：
CA2880236
公开号：
CA2880236A1
申请日:
2013.07.26
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The present invention relates to efflux inhibitor compositions and methods of using these agents for treating conditions where the activity of efflux transporter proteins (e.g., Breast Cancer Resistance Protein (BCRP) and P-Glycoprotein (P-GP)) inhibit effective delivery of a therapeutic agent to a target tissue (e.g., brain, spinal cord, nerves, cerebrospinal fluid, testis, eyeballs, retina, inner ear, placenta, mammary gland, liver, biliary tract, kidney, intestines, lung, adrenal cortex, endometrium, hematopoietic cells, and/or stem cells).
