Blood platelet function the active medicine which you control and reverse and, the composition and method are offered with the long-cherished desire bill. In the execution feature of specification, the active medicine which was offered with the long-cherished desire bill controls or reverses blood platelet function, or. In the execution feature of specification, the composition which is stated in the long-cherished desire bill is the medicine formulation. Blood platelet function the method where you control and reverse and, is offered to the long-cherished desire bill. In the execution feature of specification, the method of stating in the long-cherished desire bill includes the dosage of the Sema3E polypeptide. Furthermore, blood platelet function (namely blood platelet activation) with method of method and the screening active medicine candidacy which remedy the sick condition which it is related and is offered.血小板機能を抑制および反転させる活性薬剤、組成物および方法を本願明細書で提供する。特定の実施態様において、本願明細書で提供した活性薬剤は、血小板機能を抑制または反転させる。特定の実施態様において、本願明細書に記載した組成物は、医薬製剤である。血小板機能を抑制および反転させる方法をまた、本願明細書に提供する。特定の実施態様において、本願明細書に記載した方法はSema3Eポリペプチドの投与を含む。更に、血小板機能(すなわち血小板活性化)と関連する病態を治療する方法およびスクリーニング活性薬剤候補の方法をまた提供する。