DOSE SELECTION OF ADJUVANTED SYNTHETIC NANOCARRIERS

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专利权人:

Selecta Biosciences; Inc.

发明人:

Ilyinskii, Petr,Lipford, Grayson B.,Zepp, Charles

申请号：

AU2017201080

公开号：

AU2017201080A1

申请日:

2017.02.17

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

#$%^&*AU2017201080A120170309.pdf#####ABSTRACT Disclosed are synthetic nanocarrier compositions with coupled adjuvant compositions as well as related methods.WO 2011/150258 PCT/US2011/038210 1/9 SYSTEMIC TNF-a PRODUCTION UPON NC INOCULATION (3 MICE/GROUP) 2500----- NC-R848-1 --- v--- NC-R848-2 2000- ----- NC ONLY E -- NC ONLY+ R848 1500Z 100050001 0 1 2 3 4 5 6 TIME AFTER INJECTION (HOURS) Fig. 1 A SYSTEMIC IL-6 PRODUCTION UPON NC INOCULATION (3 MICE/GROUP) 5000--- A-- NC-R848-1 --- v--- NC-R848-2 4000- ----- NC ONLY -n-NC ONLY+ R848 E 3000i 200010000 1 2 3 4 5 6 7 TIME AFTER INOCULATION (HRS) Fig. 1B

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