Transglutaminase conjugation method and linker

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专利权人:

Paul Scherrer Institut

发明人:

SPYCHER, Philipp,SCHIBLI, Roger,BEHE, Martin,WEHRMÜLLER, Jöri

申请号：

AU2018337671

公开号：

AU2018337671A1

申请日:

2018.09.19

申请国别(地区):

AU

年份:

2020

代理人:

摘要：

The present invention relates to a method for generating an antibody-payload conjugate by means of a microbial transglutaminase (MTG). The method comprises a step of conjugating a linker having a primary amine residue, said linker having the peptide structure (shown in N->；C direction) (Aax)

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/