William G. Austen, JR.,Michael McCormack,Robert W. Redmond,Irene E. Kochevar
申请号:
US16686691
公开号:
US20200078159A1
申请日:
2019.11.18
申请国别(地区):
US
年份:
2020
代理人:
摘要:
One aspect of the invention provides a method of preventing or reducing stenosis in a subject. The method includes implanting a passivated graft comprising vein into an artery. The implanting of the graft replaces and/or bypasses a diseased segment of the artery. The passivated graft including vein is prepared by exposing the exterior surface of the passivated graft comprising vein to a tissue structure stabilizing agent (“TSSA”) under conditions sufficient to promote cross-linking of proteins within the vein.