Formulations of antimicrobial, antiviral, and antineoplastic compounds in combination with certain wavelengths of light include a solution that includes an oxidizer the solution having an initial therapeutic effectiveness and a light of a predetermined frequency that that undergoes a synergistic reaction with the oxidizer, thereby enhancing the initial therapeutic effectiveness of the solution. A method of drug-enhancement includes providing a drug that includes hydrogen peroxide and a therapeutic chemical, the drug having an initial therapeutic effectiveness and applying light having a predetermined frequency of light that has a synergistic reaction with the drug, thereby enhancing the initial therapeutic effectiveness of the drug.