In the gearwheel which at least possesses the crown various homoplastic transplantation technology (in vivo culture) without using, in vitro (in vitro culture) in, offer of the regenerative gearwheel which was formed by manner, and the said manner which at least can form the dental root. At least, in the gearwheel which possesses the crown, being the manner which at least forms the dental root, the aforementioned gearwheel, it cultures the core formation process for culture and the core for aforementioned culture which form the core for culture which was wrapped with the cell content backing material which includes at least each cell of the dental root film origin cell, the marrow origin cell, the gearwheel sacculus origin cell, the gearwheel medulla origin cell, and the gearwheel papillar origin cell, in the culture solution, it includes with the process which at least forms the dental root in the gearwheel in the core for aforementioned culture, the aforementioned culture solution, has the specified component.異種・同種移植技術(生体内培養)を使用することなく、インビトロ(生体外培養)において、少なくとも歯冠を有する歯に、少なくとも歯根を形成することができる方法、及び該方法により形成された再生歯の提供。少なくとも歯冠を有する歯に、少なくとも歯根を形成する方法であって、前記歯を、歯根膜由来細胞、骨髄由来細胞、歯小嚢由来細胞、歯髄由来細胞、及び歯乳頭由来細胞の少なくともいずれかの細胞を含む細胞含有基材で包んだ培養用コアを形成する培養用コア形成工程と、前記培養用コアを、培養液中で培養し、前記培養用コア中の歯に少なくとも歯根を形成する工程とを含み、前記培養液が、所定の成分を有する。
