A method includes visually presenting image data (404) in a main window (402) of a display monitor (120). The image data is processed with a first processing algorithm. The method further includes identifying tissue of interest in the image data displayed in the main window. The method further includes generating, with the processor (124), a sub-viewport (502) for the tissue of interest by determining at least one of: a location of the sub-viewport； a size of the sub-viewport； a shape of the sub-viewport； or an orientation of the sub-viewport. The method further includes visually presenting the sub-viewport over a sub-region of the image data in the main window based on one or more of the location, the size, the shape, or the orientation.
