An automatic injector includes a housing having a guide, a drive control mechanism, a transmission assembly, a motor, and an energy source. The housing may further include a cartridge cover. A drive control mechanism includes a drive screw, a cartridge carrier, a plunger carrier, and one or more control transfer instruments, such as a puck or cylinder. The drive screw interfaces and connects with the plunger carrier. The automatic injector is configured to accept a variety of syringes as cartridges for drug delivery. The cartridges may be ejected from the injector and safely disposed after use, making the injector a reusable automatic injector. The reusable automatic injector may further include one or more sensors, such as a cartridge sensor and a patient sensor. The novel incorporation of the drive control mechanisms into the automatic injectors of the present invention enables a single motor and transmission assembly to drive the function of multiple components, which may include the steps of: preparation and alignment of a cartridge for injection, removal of a safety cap or needle shield, needle injection, drug dose delivery, and syringe and/or needle retraction. Methods of manufacture and methods of use are also disclosed.La présente invention concerne un injecteur automatique (50) qui comprend un boîtier (52, 236) ayant un guide (158), un mécanisme de commande d'entraînement, un ensemble de transmission (110), un moteur (106), et une source d'énergie. Le boîtier (52, 236) peut comprendre en outre un couvercle de cartouche (72). Un mécanisme de commande d'entraînement comprend une vis d'entraînement (114), un support de cartouche (126, 202), un support de piston (138, 194, 226, 242), et un ou plusieurs instruments de transfert de commande (150, 204), tels qu'une rondelle ou un cylindre. La vis d'entraînement (114) est interfacée et raccordée avec le support de piston (138, 194, 226, 242). L'injecteur automatique (50) est configuré pour accepter différentes se
