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TREATMENT AND PREVENTION OF CARDIOVASCULAR DISEASE AND THROMBOSIS
专利权人:
The Cleveland Clinic Foundation
发明人:
Stanley L. Hazen,Bruce Levison,Zeneng Wang
申请号:
US13915299
公开号:
US20130345171A1
申请日:
2013.06.11
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Provided herein are compositions for the treatment and/or prevention of cardiovascular disease (CVD), and methods of application and use thereof. In particular, the present invention provides treatment and/or prevention of cardiovascular disease with compounds that inhibit the production of TMA in the gut, such as 3,3-dimethyl-1-butanol (DMB) or other compounds represented by Formula I or as shown in FIGS. 20-23.
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