In the present invention there is provided an oral pharmaceutical composition, comprising bendamustine or a pharmaceutically acceptable, ester, salt or solvate thereof as an active ingredient, and a pharmaceutically acceptable excipient, which is a pharmaceutically acceptable non-ionic hydrophilic surfactant.La présente invention concerne une composition pharmaceutique orale, contenant de la bendamustine ou l'un de ses esters, sels ou solvates pharmaceutiquement acceptables en tant que principe actif, et un excipient pharmaceutiquement acceptable qui est un agent tensioactif hydrophile non ionique pharmaceutiquement acceptable.