The present invention relates to medical devices and, in particular, to optical computing devices configured to monitor cardiac-related conditions. One optical computing device includes a substrate, at least one light source mounted on the substrate and configured to emit electromagnetic radiation that optically interacts with a vasculature and generates an optically interacted signal, a plurality of detectors mounted on the substrate and configured to detect the optically interacted signal, and a stabilizing matrix arranged on the substrate and substantially surrounding the at least one light source and the plurality of detectors. The stabilizing matrix may be configured to absorb vibration and thereby reduce motion artifacts detectable by the plurality of detectors.
