The embodiment of the proposed invention relates to prefilled syringe containing Clonidine whereby drug dosage is administered aseptically. The present syringe contains Clonidine in required dosage quantity and concentration and thereby eliminates the requirement of filing of Clonidine from the vials into the syringe. This further eliminates the risk of exposure of the drug to the atmosphere and thereby further eliminates the risk of contamination. This enables aseptic drug delivery and thereby eliminates the risk of further medical complications. Also the dilution and dosage errors are avoided. The present syringe contains pre-diluted Clonidine wherein the diluting solutions are not required to be handled separately. Also, the Clonidine vials are not required to be separately handled. This makes handling of the present syringes easy.