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Methods of inhibiting the binding of P-selectin to PSGL-1 with anti-P-selectin antibodies
专利权人:
Hoffmann-La Roche Inc.
发明人:
Yvo Graus,Jacques Himber,Miranda Jansen-Molenaar,Dorothee Kling,Erhard Kopetzki,Paul Parren,Frank Rebers,Beat Steiner,Anne Stern,Pamela Braemer,Kay-Gunnar Stubenrauch,Jan van de Winkel,Martine van Vug
申请号:
US13653597
公开号:
USRE044389E1
申请日:
2012.10.17
申请国别(地区):
US
年份:
2013
代理人:
摘要:
This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a benefit for a patient suffering from critical limb ischemia or peripheral arterial occlusive disease (CLI/PAOD).
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中国工程科技知识中心
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