Yvo Graus,Jacques Himber,Miranda Jansen-Molenaar,Dorothee Kling,Erhard Kopetzki,Paul Parren,Frank Rebers,Beat Steiner,Anne Stern,Pamela Braemer,Kay-Gunnar Stubenrauch,Jan van de Winkel,Martine van Vug
申请号:
US13653597
公开号:
USRE044389E1
申请日:
2012.10.17
申请国别(地区):
US
年份:
2013
代理人:
摘要:
This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a benefit for a patient suffering from critical limb ischemia or peripheral arterial occlusive disease (CLI/PAOD).