UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
发明人:
Larisa J. Geskin,Brittany Lynn O'Neill Dulmage,Louis D. Falo, JR.
申请号:
US16581959
公开号:
US20200033348A1
申请日:
2019.09.25
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to biomarkers associated with CTCL, including TOX, PLS3, KIR3DL2, GATA3 and RUNX3, where increased expression, relative to normal control, of one or more of TOX, PLS3, KIR3DL2, and/or GATA3 is associated with CTCL and decreased expression of RUNX3, relative to normal control, is associated with CTCL. One or more of these biomarkers may be used to diagnose CTCL and/or design and monitor treatment.