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Solid dispersion with improved solubility comprising tetrazole derivative as an active ingredient
专利权人:
发明人:
KIM YONG IL,CHOI JUN YOUNG,CHOI YOUNG KEUN,PARK JAE HYUN,WOO JONG SOO
申请号:
IN4963/DELNP/2015
公开号:
IN2015DN04963A
申请日:
2015.06.09
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
The present invention relates to an amorphous solid dispersion comprising a tetrazole derivative of the formula (I) or a pharmaceutically acceptable salt thereof as an active ingredient. The solid dispersion of the present invention comprises a water- soluble polymer or an acid so as to improve the solubility of its active ingredient, i.e., the tetrazole derivative of the formula (I) , thereby improving its absorption rate , and thus can be effectively used to reduce multi- drug resistance (MDR) in cancer cells.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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